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Cetirizine Impurity Q

Synonyms: Cetirizine Glycerol Ester Dihydrochloride(Mixture of Diastereomers);2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-2,3-dihydroxypropyl Ester Acetic Acid;
Cat. No.: C28020 CAS No.: Free amine: 1243652-36-9
MDL.: Formula: C24H33Cl3N2O5
F.W. 535.89 Purity: 99%
Storage: at -20°C Freezer
 
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Catalog Number: C28020   CAS No.: Free amine: 1243652-36-9
MDL: Formula: C24H33Cl3N2O5
F.W.: 535.89 Purity: 99%
Package: Unit: mg
Appearance: Off-White to Pale Tan Solid M.P.: 131-136°C
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO, Methanol, Water Stability:
Storage: at -20°C Freezer Category: Reference Standard
Reference: De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
Application: Cetirizine glycerol ester is an impurity in the synthesis of Cetirizine , a non-sedating type histamine H1-receptor antagonist whose activity lies in the (R) Isomer primarily.
Category: Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,