Cetirizine Impurity Q |
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Synonyms: Cetirizine Glycerol Ester Dihydrochloride(Mixture of Diastereomers);2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-2,3-dihydroxypropyl Ester Acetic Acid; | |
Cat. No.: C28020 | CAS No.: Free amine: 1243652-36-9 |
MDL.: | Formula: C24H33Cl3N2O5 |
F.W. 535.89 | Purity: 99% |
Storage: at -20°C Freezer | |
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Catalog Number: | C28020 | CAS No.: | Free amine: 1243652-36-9 | |
MDL: | Formula: | C24H33Cl3N2O5 | ||
F.W.: | 535.89 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | Off-White to Pale Tan Solid | M.P.: | 131-136°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO, Methanol, Water | Stability: | ||
Storage: | at -20°C Freezer | Category: | Reference Standard | |
Reference: | De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987) | |||
Application: | Cetirizine glycerol ester is an impurity in the synthesis of Cetirizine , a non-sedating type histamine H1-receptor antagonist whose activity lies in the (R) Isomer primarily. | |||
Category: | Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, |