Cetirizine Impurity B |
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Synonyms: 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineacetic Acid;De(carboxymethoxy) Cetirizine Acetic Acid; (RS)-2-[4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl]acetic acid; EP Cetirizine Impurity B | |
Cat. No.: C28004 | CAS No.: 113740-61-7 |
MDL.: | Formula: C19H21ClN2O2 |
F.W.344.84 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | C28004 | CAS No.: | 113740-61-7 | |
MDL: | Formula: | C19H21ClN2O2 | ||
F.W.: | 344.84 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | No Data Available | M.P.: | No Data Available | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | No Data Available | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | De Vos, C., et al.: Ann. Allergy, 59, 278 (1987); Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987); Fadel, R., et al.: Clin. Allergy, 17, 373 (1987); Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987) | |||
Application: | De(carboxymethoxy) Cetirizine Acetic Acid is an impurity of Cetirizine ( 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine. Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also ant | |||
Category: | Amines, Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |