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(R)-Cetirizine Dihydrochloride

Synonyms: 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid Dihydrochloride; (-)-Cetirizine Dihydrochloride; Levocetirizine Dihydrochloride;
Cat. No.: C28002 CAS No.: 130018-77-8
MDL.: Formula: C21H27Cl3N2O3
F.W.461.81 Purity: 99%
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
 
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Catalog Number: C28002   CAS No.: 130018-77-8
MDL: Formula: C21H27Cl3N2O3
F.W.: 461.81 Purity: 99%
Package: Unit: mg
Appearance: Off-White Solid M.P.: 205-208°C (dec.)
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO, Methanol, Water Stability:
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere Category: Reference Standard
Reference: De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
Application: A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
Category: Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,