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Zileuton Impurity B-d10

Synonyms: Benzo[b]thien-2-yl Ketone-D10;Bis(benzo[b]thien-2-yl)methanone-D10;
Cat. No.: Z73432 CAS No.: Unlabelled: 97978-07-9
MDL.: Formula: C17D10OS2
F.W.304.45 Purity: 99%
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Catalog Number: Z73432   CAS No.: Unlabelled: 97978-07-9
MDL: Formula: C17D10OS2
F.W.: 304.45 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Israel, E., et al.: JAMA, 275, 931 (1996); Mahboobi, S., et al.: J. Med. Chem., 45, 1002 (2002); Mitschke, U. & Bäuerle, P.: J. Chem. Soc. Perk. Trans., 1, 740 (2001); Nenajdenko, V., et al.: Russ. Chem. Bull., 61, 1456 (2012)
Application: Benzo[b]thien-2-yl ketone-D10 is a labelled analogue of Benzo[b]thien-2-yl ketone. Benzo[b]thien-2-yl ketone is an impurity of Zileuton, an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. Benzo[b]thien-2-yl ketone is used as a reagent to synthesize Bis(1H-2-indolyl)methanone, compounds that inhibit the activity of growth factor receptor kinase. Benzo[b]thien-2-yl ketone is also used as a reagent to prepare annulated oligothiophenes, compounds that are used in organic light-emitting devides (OLEDs).
Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Sulfur and Selenium Compounds