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Sacubitril Impurity H
Synonyms: (3R,5S)-rel-5-([1,1’-biphenyl]-4-ylmethyl)-3-methyl-2-Pyrrolidinone; (3R,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one
Cat. No.: S00313	CAS No.: 2101222-51-7/1038924-70-7( absolute stereochemistry)
MDL.:	Formula: C18H19NO
F.W.265.35	Purity: 99％
Storage: Refrigerator

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Catalog Number：	S00313		CAS No.:	2101222-51-7/1038924-70-7( absolute stereochemistry)
MDL:			Formula:	C18H19NO
F.W.:	265.35		Purity:	99％
Package:			Unit:	mg
Appearance:	White to Off-White Solid		M.P.:	148-150°C
B.P.:			Density:	1.083±0.06 g/cm3 (20 ºC 760 Torr), Calc.*
Optical Rotation:			Refractive Index:
Solubility:	Chloroform (Slightly), Methanol (Slightly)		Stability:
Storage:	Refrigerator		Category:	Reference Standard
Reference:	McMurray, J., et al.: N. Eng. J. Med., 371 (2014); Xu, X., et al.: Process for preparation of Sacubitril, CN 104557600, Apr 29, 2015;
Application:	Sacubitril Impurity 1 is an impurity of Sacubitril which is an antihypertensive drug used in combination with valsartan.
Category:	Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals

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