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Baclofen Impurity C

Synonyms: 1-Cyanotetraline;1,2,3,4-Tetrahydro-1-naphthalenecarbonitrile; 1,2,3,4-Tetrahydro-1-naphthonitrile; 1,2,3,4-Tetrahydro-1-naphthalenecarbonitrile; 1-Cyano-1,2,3,4-tetrahydronaphthalene; 1-Cyanotetralin
Cat. No.: B00207 CAS No.: 56536-96-0
MDL.: Formula: C11H11N
F.W.157.21 Purity: 99%
Storage: Room Temp
 
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Catalog Number: B00207   CAS No.: 56536-96-0
MDL: Formula: C11H11N
F.W.: 157.21 Purity: 99%
Package: Unit: g
Appearance: Clear Yellow Oil M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly Stability:
Storage: Room Temp Category: Reference Standard
Reference: Sarges, R. et al.: J. Med. Chem., 31, 230 (1988); Mann, A. et al.: J. Med. Chem., 34, 1307 (1991);
Application: 1-Cyanotetraline is used in the synthesis of aldose reductase inhibitors. Also reductase enzymes are believed to catalyze the formation of sorbitol from glucose leading to the chronic complications of diabetes mellitus. It is also used in the synthesis of baclofen analogs, potent GABAB agonists.
Category: Aromatics, Miscellaneous Reagents