| Catalog Number： |
A50033 |
|
CAS No.: |
444904-63-6 |
| MDL: |
|
|
Formula: |
C8H7Cl2N3 |
| F.W.: |
216.07 |
|
Purity: |
99％ |
| Package: |
|
|
Unit: |
mg |
| Appearance: |
Light Yellow to Yellow Solid |
|
M.P.: |
205-208°C |
| B.P.: |
|
|
Density: |
|
| Optical Rotation: |
|
|
Refractive Index: |
|
| Solubility: |
DMSO (Slightly), Methanol (Slightly) |
|
Stability: |
|
| Storage: |
Hygroscopic, -20°C Freezer, Under inert atmosphere |
|
Category: |
Reference Standard |
| Reference: |
Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979); Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984); Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988); Spencer, C.M., et al.: Drugs, 47, 809 (1994) |
| Application: |
2-Amino-5,6-dichloro-3,4-dihydroquinazoline is a metabolite of Anagrelide, a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. |
| Category: |
Amines, Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |
