Almotriptan Impurity B (2E)-2-Butenedioate |
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Synonyms: 5-[(1-Pyrrolidinylsulfonyl)Methyl]-1H-Indole-3-Ethanamine (2E)-2-Butenedioate; Almotriptan USP Related Compound B (2E)-2-Butenedioate | |
Cat. No.: A34004 | CAS No.: 1246860-65-0/181178-24-5(free ) |
MDL.: | Formula: C15H21N3O2S • x(C4H4O4) |
F.W.307.41 + x(116.07) | Purity: 99% |
Storage: | |
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Catalog Number: | A34004 | CAS No.: | 1246860-65-0/181178-24-5(free ) | |
MDL: | Formula: | C15H21N3O2S • x(C4H4O4) | ||
F.W.: | 307.41 + x(116.07) | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003) | |||
Application: | 5-[(1-Pyrrolidinylsulfonyl)Methyl]-1H-Indole-3-Ethanamine (2E)-2-Butenedioate used in the preparation of almotriptan and its salts by cyclocondensation of chlorobutyraldehyde acetal with (hydrazinylbenzylsulfonyl)pyrrolidine. | |||
Category: | Amines,Aromatics, Heterocycles, Metabolites & Impurities, Indole Derivatives,Pharmaceuticals, Intermediates & Fine Chemicals,Sulfur & Selenium Compounds |