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Adapalene Intermediate K

Synonyms: 2-(1-Adamantyl)-4-bromophenol; 4-Bromo-2-(1-adamantyl)phenol; 2-((3r,5r,7r)-Adamantan-1-yl)-4-bromophenol;2-(Adamantan-1-yl)-4-bromophenol
Cat. No.: A07040 CAS No.: 104224-68-2
MDL.: Formula: C16H19BrO
F.W.307.23 Purity: 99%
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Catalog Number: A07040   CAS No.: 104224-68-2
MDL: Formula: C16H19BrO
F.W.: 307.23 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Sokolenko, V.A., et. al.: Pharmaceut. Chem. J., 47, 217 (2013); Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993); Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993); Waugh, J., et al.: Drugs, 64, 1465 (2004)
Application: 2-(Adamantan-1-yl)-4-bromophenol is an intermediate in the synthesis of Adapalene, a retinoid selective for retinoic acid receptor (RAR) subtypes ß and ?; an antiacne agent
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals