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Adapalene Intermediate I

Synonyms: Methyl 6-(4-Methoxyphenyl)-2-naphthoate;6-(4-Methoxyphenyl)-2-naphthalenecarboxylic Acid Methyl Ester; 6-(4-Methoxyphenyl)-2-naphthoic Acid Methyl Ester
Cat. No.: A07038 CAS No.: 128272-36-6
MDL.: Formula: C19H16O3
F.W.292.33 Purity: 99%
Storage: Room Temp
 
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Catalog Number: A07038   CAS No.: 128272-36-6
MDL: Formula: C19H16O3
F.W.: 292.33 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Room Temp Category: Reference Standard
Reference: Milanese, A., et. al.: Bioorg. Chem., 39, 151 (2011); Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993); Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993); Waugh, J., et al.: Drugs, 64, 1465 (2004)
Application: Methyl 6-(4-Methoxyphenyl)-2-naphthoate is used in the synthesis of Adapalene, a retinoid selective for retinoic acid receptor (RAR) subtypes ß and ?. Antiacne
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals