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Adapalene Impurity I

Synonyms: 4-Bromo-2-((1S,2S,5S)-2-(5-bromo-2-methoxyphenyl)adamantan-1-yl)phenol
Cat. No.: A07009 CAS No.: N.A.
MDL.: Formula: C23H24Br2O2
F.W.492.24 Purity: 99%
Storage: Room Temp
 
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Catalog Number: A07009   CAS No.: N.A.
MDL: Formula: C23H24Br2O2
F.W.: 492.24 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Room Temp Category: Reference Standard
Reference: Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993); Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993); Waugh, J., et al.: Drugs, 64, 1465 (2004)
Application: 4-Bromo-2-((1S,2S,5S)-2-(5-bromo-2-methoxyphenyl)adamantan-1-yl)phenol is an impurity in the synthesis of Adapalene, a retinoid selective for retinoic acid receptor (RAR) subtypes ß and ?. Antiacne.
Category: Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals