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Risperidone Intermediate A2

Synonyms: 1-Bromo-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-4-fluoro-benzene
Cat. No.: R56102 CAS No.: 1178513-66-0
MDL.: Formula: C22H22BrFOSi
F.W.429.4 Purity: 99%
Storage: Room Temperature
 
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Catalog Number: R56102   CAS No.: 1178513-66-0
MDL: Formula: C22H22BrFOSi
F.W.: 429.4 Purity: 99%
Package: Unit:
Appearance: White Solid M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Hexane; Stability:
Storage: Room Temperature Category: Reference Standard
Reference: Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988); Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990); Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)
Application: 1-Bromo-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-4-fluoro-benzene is an intermediate used in the synthesis of Bicyclo Risperidone, which is an impurity of Risperidone; a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
Category: Amines, Heterocycles;Pharmaceuticals, Intermediates & Fine Chemicals,