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Risperidone Intermediate Y

Synonyms: (2S)-3,4-Dihydro-2H-1-benzopyran-2-carbonyl Chloride
Cat. No.: R56099 CAS No.: 130049-78-4
MDL.: Formula: C10H9ClO2
F.W.196.63 Purity: 99%
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Catalog Number: R56099   CAS No.: 130049-78-4
MDL: Formula: C10H9ClO2
F.W.: 196.63 Purity: 99%
Package: Unit:
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Optical Rotation: Refractive Index:
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Storage: Category: Reference Standard
Reference: Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005)
Application: (2S)-3,4-Dihydro-2H-1-benzopyran-2-carbonyl Chloride is an intermediate used in the synthesis of (S)-9-Hydroxy Risperidone-d4 , which is the S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
Category: Chiral agents, Aromatics, Heterocycles, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals