Labetalol Intermediate S |
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Synonyms: Dimethyl 5,5'-(Pyrazine-2,5-diyl)bis(2-hydroxybenzoate) | |
Cat. No.: L00168 | CAS No.: N.A. |
MDL.: | Formula: C20H16N2O6 |
F.W.380.36 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | L00168 | CAS No.: | N.A. | |
MDL: | Formula: | C20H16N2O6 | ||
F.W.: | 380.36 | Purity: | 99% | |
Package: | Unit: | |||
Appearance: | Pale brown solid | M.P.: | ||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Dichloromethane; hot DMF | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989), | |||
Application: | Dimethyl 5,5'-(Pyrazine-2,5-diyl)bis(2-hydroxybenzoate) is an intermediate in the synthesis of 5,5'-(Piperazine-2,5-diyl)bis(2-hydroxybenzamide), which is a dimer impurity of Labetalol, a specific competitive antagonist at both a-and ß-adrenergic receptor sites. | |||
Category: | Amines, Aromatics, Heterocyles, Pharmaceuticals, Intermediates & Fine Chemicals |