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Labetalol Intermediate S

Synonyms: Dimethyl 5,5'-(Pyrazine-2,5-diyl)bis(2-hydroxybenzoate)
Cat. No.: L00168 CAS No.: N.A.
MDL.: Formula: C20H16N2O6
F.W.380.36 Purity: 99%
Storage: Refrigerator
 
Size/Unit Price Qty Availability Price Total
2.5mg $195.00 Enter qty and click checkbox $195.00
Catalog Number: L00168   CAS No.: N.A.
MDL: Formula: C20H16N2O6
F.W.: 380.36 Purity: 99%
Package: Unit:
Appearance: Pale brown solid M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Dichloromethane; hot DMF Stability:
Storage: Refrigerator Category: Reference Standard
Reference: Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989),
Application: Dimethyl 5,5'-(Pyrazine-2,5-diyl)bis(2-hydroxybenzoate) is an intermediate in the synthesis of 5,5'-(Piperazine-2,5-diyl)bis(2-hydroxybenzamide), which is a dimer impurity of Labetalol, a specific competitive antagonist at both a-and ß-adrenergic receptor sites.
Category: Amines, Aromatics, Heterocyles, Pharmaceuticals, Intermediates & Fine Chemicals