Labetalol Intermediate K |
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Synonyms: Methyl 5-(2-Aminoacetyl)-2-hydroxybenzoate p-Toluenesulfonic Acid;Methyl 5-Glycyl-2-hydroxybenzoate 4-Methylbenzenesulfonate | |
Cat. No.: L00160 | CAS No.: Free: 723733-75-3 |
MDL.: | Formula: C17H19NO7S |
F.W.381.4 | Purity: 99% |
Storage: Refrigerator, under inert atmosphere | |
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Catalog Number: | L00160 | CAS No.: | Free: 723733-75-3 | |
MDL: | Formula: | C17H19NO7S | ||
F.W.: | 381.4 | Purity: | 99% | |
Package: | Unit: | |||
Appearance: | White solid | M.P.: | ||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Methanol; DMSO | Stability: | ||
Storage: | Refrigerator, under inert atmosphere | Category: | Reference Standard | |
Reference: | Sybertz, E.J., et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981), Clifton, J.E., et al.: J. Med. Chem., 25, 670 (1982), Goa, K.L., et al.: Drugs, 37, 583 (1989), | |||
Application: | Methyl 5-(2-Aminoacetyl)-2-hydroxybenzoate p-Toluenesulfonic Acid is an intermediate in the synthesis of 5,5'-(Piperazine-2,5-diyl)bis(2-hydroxybenzamide)which is a dimer impurity of Labetalol, a specific competitive antagonist at both a-and ß-adrenergic receptor sites. | |||
Category: | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |