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Labetalol Intermediate D

Synonyms: 5-(Benzylglycyl)-2-hydroxybenzamide Hydrochloride;2-Hydroxy-5-[2-[(phenylmethyl)amino]acetyl]-benzamide Hydrochloride
Cat. No.: L00153 CAS No.: Free: 901376-13-4
MDL.: Formula: C16H17ClN2O3
F.W.320.78 Purity: 99%
Storage: Refrigerator
 
Size/Unit Price Qty Availability Price Total
10mg $150.00 Enter qty and click checkbox $150.00
Catalog Number: L00153   CAS No.: Free: 901376-13-4
MDL: Formula: C16H17ClN2O3
F.W.: 320.78 Purity: 99%
Package: Unit:
Appearance: Yellow solid M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO Stability:
Storage: Refrigerator Category: Reference Standard
Reference: Sybertz, E.J. et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981); Clifton, J.E. et al.: J. Med. Chem., 25, 670 (1982); Goa, K.L. et al.: Drugs, 37, 583 (1989);
Application: 2-Hydroxy-5-[2-[(phenylmethyl)amino]acetyl]-benzamide Hydrochloride is an intermediate in the synthesis of 5-(2-(Benzylamino)-1-hydroxyethyl)-2-hydroxybenzamide which is an impurity of Labetalol, a specific competitive antagonist at both a-and ß-adrenergic receptor sites. Labetalol is used as an antihypertensive.
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals