Labetalol Intermediate D |
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| Synonyms: 5-(Benzylglycyl)-2-hydroxybenzamide Hydrochloride;2-Hydroxy-5-[2-[(phenylmethyl)amino]acetyl]-benzamide Hydrochloride | |
| Cat. No.: L00153 | CAS No.: Free: 901376-13-4 |
| MDL.: | Formula: C16H17ClN2O3 |
| F.W.320.78 | Purity: 99% |
| Storage: Refrigerator | |
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| Catalog Number: | L00153 | CAS No.: | Free: 901376-13-4 | |
| MDL: | Formula: | C16H17ClN2O3 | ||
| F.W.: | 320.78 | Purity: | 99% | |
| Package: | Unit: | |||
| Appearance: | Yellow solid | M.P.: | ||
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | DMSO | Stability: | ||
| Storage: | Refrigerator | Category: | Reference Standard | |
| Reference: | Sybertz, E.J. et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981); Clifton, J.E. et al.: J. Med. Chem., 25, 670 (1982); Goa, K.L. et al.: Drugs, 37, 583 (1989); | |||
| Application: | 2-Hydroxy-5-[2-[(phenylmethyl)amino]acetyl]-benzamide Hydrochloride is an intermediate in the synthesis of 5-(2-(Benzylamino)-1-hydroxyethyl)-2-hydroxybenzamide which is an impurity of Labetalol, a specific competitive antagonist at both a-and ß-adrenergic receptor sites. Labetalol is used as an antihypertensive. | |||
| Category: | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals | |||








