Nadolol Derivative B |
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Synonyms: N-Nitrosonadolol;5-[3-[(1,1-Dimethylethyl)nitrosoamino]-2-hydroxypropoxy]-1,2,3,4-tetrahydro-2,3-naphthalenediol | |
Cat. No.: N01021 | CAS No.: 134720-06-2/42200-33-9(parent)-2/42200-33-9(parent) |
MDL.: | Formula: C17H26N2O5 |
F.W.338.4 | Purity: 99% |
Storage: -20°C Freezer, Under inert atmosphere | |
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Catalog Number: | N01021 | CAS No.: | 134720-06-2/42200-33-9(parent)-2/42200-33-9(parent) | |
MDL: | Formula: | C17H26N2O5 | ||
F.W.: | 338.4 | Purity: | 99% | |
Package: | Unit: | |||
Appearance: | White to Off-White Solid | M.P.: | 128-130°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO (Slightly), Methanol (Slightly) | Stability: | ||
Storage: | -20°C Freezer, Under inert atmosphere | Category: | Reference Standard | |
Reference: | Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977), Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978), Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980); Martelli, A., In Vivo, 11, 189-194, (1997); | |||
Application: | N-Nitrosonadolol is an N-nitroso derivative of Nadolol,which is a ß-Adrenergic blocker, antihypertensive, and antianginal. N-Nitrosonadolol can be used to assess genotoxicity in human and rat hepatocytes. | |||
Category: | Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |