| Catalog Number： |
A44512 |
|
CAS No.: |
3027-38-1 |
| MDL: |
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|
Formula: |
C12H5NO5 |
| F.W.: |
243.17 |
|
Purity: |
99％ |
| Package: |
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|
Unit: |
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| Appearance: |
Pale Yellow to Light Yellow Solid |
|
M.P.: |
249-250°C |
| B.P.: |
|
|
Density: |
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| Optical Rotation: |
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Refractive Index: |
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| Solubility: |
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
|
Stability: |
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| Storage: |
at -20°C Freezer, Under inert atmosphere |
|
Category: |
Reference Standard |
| Reference: |
Haishi, C., et al.: Org. Lett., 4, 1503 (2002); Ingrassia, L., et al.: Curr. Med. Chem., 16, 1192 (2009); |
| Application: |
3-Nitro-1,8-naphthalic anhydride is a reagent used to synthesize a monoboronic acid fluorescent sensor that exhibits emission suitable for ratiometric testing and also displays sensitivity for glucose relative to fructose and galactose. 3-Nitro-1,8-naphthalic anhydride is also used as a starting reagent in the synthesis of 5-substituted naphthalimide derivatives which exhibit high anti-cancer activity.I tis also used in the synthesis of Amonafide, which is a DNA intercalator and topoisomerase II inhibitor in clinical development for the treatment. |
| Category: |
Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |
