Efavirenz Metabolite A |
|
Synonyms: rac 8-Hydroxy Efavirenz; 6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz; | |
Cat. No.: E21025 | CAS No.: 205754-32-1 |
MDL.: | Formula: C14H9ClF3NO3 |
F.W.331.67 | Purity: 99% |
Storage: -20°C Freezer | |
  |
Catalog Number: | E21025 | CAS No.: | 205754-32-1 | |
MDL: | Formula: | C14H9ClF3NO3 | ||
F.W.: | 331.67 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | White to Off-White Solid | M.P.: | 186-188°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO, Methanol | Stability: | ||
Storage: | -20°C Freezer | Category: | Reference Standard | |
Reference: | Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309 (2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003), | |||
Application: | A metabolite of Efavirenz , a nonnucleoside HIV-1 reverse transcriptase inhibitor. | |||
Category: | Anti-virals, Metabolites, Inhibitors, Non-nucleoside Reverse Transcriptase, Pharmaceuticals, Intermediates & Fine Chemicals, |