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Synonyms: 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester ;Ethyl 5-Chloro-2-(cyclobut-2-en-1-yl)-3-(trifluoromethyl)-1H-indole-1-carboxylate; Efavirenz Impurity | |
Cat. No.: E21019 | CAS No.: N.A. |
MDL.: | Formula: C16H13ClF3NO2 |
F.W.343.73 | Purity: 99% |
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Catalog Number: | E21019 | CAS No.: | N.A. | |
MDL: | Formula: | C16H13ClF3NO2 | ||
F.W.: | 343.73 | Purity: | 99% | |
Package: | Unit: | mg | ||
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B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
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Storage: | Category: | Reference Standard | ||
Reference: | Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012); | |||
Application: | 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic acid ethyl ester is synthesized from 5-chloro-2-oxindole, which is used in the preparation of novel GSK-3ß inhibitors as anticancer agents. | |||
Category: | Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |