Dasatinib Metabolite E |
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Synonyms: Hydroxymethyl Dasatinib; N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide; | |
Cat. No.: D25014 | CAS No.: 910297-58-4 |
MDL.: | Formula: C22H26ClN7O3S |
F.W.504 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | D25014 | CAS No.: | 910297-58-4 | |
MDL: | Formula: | C22H26ClN7O3S | ||
F.W.: | 504 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | White to Off-White Solid | M.P.: | 191-195°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO, Methanol | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Jaworski, T., et al.: Xenobiotica, 21, 1451 (1991),Shah, N., et al.: Science, 305, 399 (2004), O'Hare, T., et al.: Cancer Res., 65, 4500 (2005), Das, J., et al.: J. Med. Chem., 49, 6819 (2006), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008 | |||
Application: | An oxidative metabolite of Dasatinib (M24 metabolite); used in the treatment of cancers and immune diseases. | |||
Category: | Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |