Darunavir Intermedaite H |
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Synonyms: (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol; [3R-(3a,3aß,6aß)]-Hexahydrofuro[2,3-b]furan-3-ol; 3R,3AS,6aR-Hexahydrofuro[2,3-b]furan-3-ol; R,S,R-Bisfuran Alcohol | |
Cat. No.: D24037 | CAS No.: 156928-09-5 |
MDL.: | Formula: C6H10O3 |
F.W.130.14 | Purity: 99% |
Storage: Hygroscopic, Refrigerator, under inert atmosphere | |
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Catalog Number: | D24037 | CAS No.: | 156928-09-5 | |
MDL: | Formula: | C6H10O3 | ||
F.W.: | 130.14 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | ale Yellow Oil | M.P.: | ||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Chloroform (Slightly), Ethyl Acetate (Slightly, Heated) | Stability: | ||
Storage: | Hygroscopic, Refrigerator, under inert atmosphere | Category: | Reference Standard | |
Reference: | Canoy, W.L., et al.: Org. Lett., 10, 1103 (2008); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005) | |||
Application: | (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol is used as a reagent in the synthesis of Darunavir; a second generation HIV-1-protease inhibitor and antiviral agent. |