Darunavir Intermedaite A |
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Synonyms: 4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide Dihydrochloride;: 4-Amino-N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide Dihydrochloride | |
Cat. No.: D24030 | CAS No.: N.A. |
MDL.: | Formula: C20H31Cl2N3O3S |
F.W.464.45 | Purity: 99% |
Storage: | |
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Catalog Number: | D24030 | CAS No.: | N.A. | |
MDL: | Formula: | C20H31Cl2N3O3S | ||
F.W.: | 464.45 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Babu, K.R., et. al.: Indian J. Chem. B, 51B, 849 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005) | |||
Application: | 4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide Dihydrochloride is an intermediate of (1R,2S)-Darunavir, a diastereomer of Darunavir, a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. | |||
Category: | Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |