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Dabigatran Metabolite B
Synonyms: Dabigatran Acyl-ß-D-Glucuronide Trifluoroacetic Acid Salt (80%); N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-ß-alanine ß-D-Glucopyranuronosyl Ester Trifluoroacetic Acid Salt;
Cat. No.: D00131	CAS No.: N.A.
MDL.:	Formula: C33H34F3N7O11
F.W.761.66	Purity: 99％
Storage: Hygroscopic, -20˚C Freezer, Under Inert Atmosphere

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Catalog Number：	D00131		CAS No.:	N.A.
MDL:			Formula:	C33H34F3N7O11
F.W.:	761.66		Purity:	99％
Package:			Unit:	mg
Appearance:	Off-White Solid		M.P.:	>155°C (dec.)
B.P.:			Density:
Optical Rotation:			Refractive Index:
Solubility:	DMSO, Methanol (Sparingly)		Stability:
Storage:	Hygroscopic, -20˚C Freezer, Under Inert Atmosphere		Category:	Reference Standard
Reference:	Becker, B., et al.: Biochem. J., 314, 249 (1996), Bailey, M., et al.: Chem. Biol. Interact., 145, 117 (2004), Blech, S., et al.: Drug Metab. Dispos., 2008, 36, 386 (2008),
Application:	The major metabolite of Dabigatran in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (ß anomer)
Category:	Aromatics, Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals

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