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Cinacalcet Intermediate J

Synonyms: 1-(3-Bromopropyl)-3-(trifluoromethyl)benzene;1-Bromo-3-[3-(trifluoromethyl)phenyl]propane
Cat. No.: C40059 CAS No.: 129254-76-8
MDL.: Formula: C10H10BrF3
F.W.267.09 Purity: 99%
Storage: Refrigerator
 
Size/Unit Price Qty Availability Price Total
25mg $75.00 Enter qty and click checkbox $75.00
Catalog Number: C40059   CAS No.: 129254-76-8
MDL: Formula: C10H10BrF3
F.W.: 267.09 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DCM, Methanol Stability:
Storage: Refrigerator Category: Reference Standard
Reference: Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003); Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004); Yu, J., et al.: Faming Zhuanli Shenqing, CN 104774134 A, 20150715 (2015)
Application: 1-(3-Bromopropyl)-3-(trifluoromethyl)benzene is a key intermediate in the synthesis of Cinacalcet Hydrochloride. Cinacalcet Hydrochloride is the (R) enantiomer of Cinacalcet and is used in clinical trial in secondary hyperparathyroidism.
Category: Aromatics, Miscellaneous Reagents