Cinacalcet Impurity K |
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Synonyms: (aR)-N-[3-[3-(Difluoromethyl)phenyl]propyl]-a-methyl-1-naphthalenemethanamine | |
Cat. No.: C40016 | CAS No.: 1025064-41-8 |
MDL.: | Formula: C22H23F2N |
F.W.339.42 | Purity: 99% |
Storage: No Data Available | |
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Catalog Number: | C40016 | CAS No.: | 1025064-41-8 | |
MDL: | Formula: | C22H23F2N | ||
F.W.: | 339.42 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | No Data Available | M.P.: | No Data Available | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | No Data Available | Stability: | ||
Storage: | No Data Available | Category: | Reference Standard | |
Reference: | Block, G. A., et al.: N. Engl. J. Med., 350, 1516 (2004); Cunningham, J., et al.: Kidney Int., 68, 1793 (2005); Peacock, M., et al.: J. Clin. Endocr. Metab., 90 (2005); Lindberg, J. S., et al.: J. Am. Soc. Nephrol., 16, 800 (2005) | |||
Application: | (aR)-N-[3-[3-(Difluoromethyl)phenyl]propyl]-a-methyl-1-naphthalenemethanamine is an impurity of Cinacalcet; an oral calcimimetic agent that modulates the calcium-sensing receptor, reduces parathyroid hormone (PHT) secretion, and lowers serum calcium and phosphorus concentrations in patients with endstage renal disease (ESRD) and secondary hyperparathyroidism (HPT). | |||
Category: | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |