| Catalog Number: |
A86048 |
|
CAS No.: |
886230-77-9 |
| MDL: |
|
|
Formula: |
C19H18IN3O |
| F.W.: |
431.27 |
|
Purity: |
99% |
| Package: |
|
|
Unit: |
mg |
| Appearance: |
White to Light Yellow Solid |
|
M.P.: |
156-159°C |
| B.P.: |
|
|
Density: |
|
| Optical Rotation: |
|
|
Refractive Index: |
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| Solubility: |
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
|
Stability: |
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| Storage: |
Amber Vial, Refrigerator |
|
Category: |
Reference Standard |
| Reference: |
Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003), |
| Application: |
(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole is an intermediate used to prepare Axitinib as a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. |
| Category: |
Aromatics, Inhibitors, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |