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Lapatinib-d7 Dihydrochloride

Synonyms: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl-d7]amino]methyl]-2-furanyl]-4-quinazolinamine Bis(4-methylbenzenesulfonate) Dihydrochloride; GW-572016F-d7 Dihydrochloride; Tykerb-d7 Dihydrochloride
Cat. No.: L12533 CAS No.: Unlabelled: 388082-77-8(free base)
MDL.: Formula: C29H21D7Cl3FN4O4S
F.W.661.02 Purity: 99%
Storage: Refrigerator
 
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Catalog Number: L12533   CAS No.: Unlabelled: 388082-77-8(free base)
MDL: Formula: C29H21D7Cl3FN4O4S
F.W.: 661.02 Purity: 99%
Package: Unit: mg
Appearance: Yellow Solid M.P.: >214°C (dec.)
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO, Methanol Stability:
Storage: Refrigerator Category: Reference Standard
Reference: Kim, T.E., et al.: Drugs, 6, 886 (2003); Wood, E.R., et al.: Cancer Res., 64, 6652 (2004); Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005)
Application: Lapatinib-d7 Dihydrochloride is a labeled Lapatinib, a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.
Category: Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors