Lapatinib Impurity B |
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| Synonyms: N-De[2-(methylsulfonyl)ethyl] Lapatinib; N-De[2-(methylsulfonyl)ethyl] Lapatinib; 6-[5-(Aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-4-quinazolinamine; [6-(5-Aminomethylfuran-2-yl)quinazolin-4-yl][3-chloro-4-(3-fluorobenzyloxy)p | |
| Cat. No.: L12505 | CAS No.: 697299-82-4 |
| MDL.: | Formula: C26H20ClFN4O2 |
| F.W.474.91 | Purity: 99% |
| Storage: No Data Available | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 1mg | POA | Enter qty and click checkbox |
| Catalog Number： | L12505 | CAS No.: | 697299-82-4 | |
| MDL: | Formula: | C26H20ClFN4O2 | ||
| F.W.: | 474.91 | Purity: | 99% | |
| Package: | Unit: | mg | ||
| Appearance: | No Data Available | M.P.: | No Data Available | |
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | No Data Available | Stability: | ||
| Storage: | No Data Available | Category: | Reference Standard | |
| Reference: | He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009), | |||
| Application: | A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites. | |||
| Category: | Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds | |||