Lapatinib Impurity A Ditosylate |
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| Synonyms: O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt;2-Chloro-4-[[6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinyl]amino]phenol Ditosylate | |
| Cat. No.: L12504 | CAS No.: Free base :1268997-70-1 |
| MDL.: | Formula: C36H37ClN4O10S3 |
| F.W.817.35 | Purity: 99% |
| Storage: -20˚C Freezer | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 1mg | POA | Enter qty and click checkbox |
| Catalog Number： | L12504 | CAS No.: | Free base :1268997-70-1 | |
| MDL: | Formula: | C36H37ClN4O10S3 | ||
| F.W.: | 817.35 | Purity: | 99% | |
| Package: | Unit: | mg | ||
| Appearance: | Yellow Solid | M.P.: | >176°C (dec.) | |
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | DMSO, Methanol | Stability: | ||
| Storage: | -20˚C Freezer | Category: | Reference Standard | |
| Reference: | He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009), | |||
| Application: | A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites. | |||
| Category: | Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds | |||