Lacosamide Impurity I |
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Synonyms: 2-(Acetylamino)-N-(phenylmethyl)-2-propenamide; Lacosamide Impurity; 2-Acetamido-N-benzylacrylamide; Lacosamide Impurity 1 | |
Cat. No.: L00710 | CAS No.: 86921-49-5 |
MDL.: | Formula: C12H14N2O2 |
F.W.218.25 | Purity: 99% |
Storage: No Data Available | |
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Catalog Number: | L00710 | CAS No.: | 86921-49-5 | |
MDL: | Formula: | C12H14N2O2 | ||
F.W.: | 218.25 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | No Data Available | Stability: | ||
Storage: | No Data Available | Category: | Reference Standard | |
Reference: | Lees, G., et al.: Brain Res., 612, 190 (1993); Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997); Barton, M., et al.: Epilepsy Res., 47, 217 (2001); Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007); Suzen, S., et al.: J. Enzym. Inhib. Med. Ch., 21, 179 (2006); | |||
Application: | 2-(Acetylamino)-N-(phenylmethyl)-2-propenamide is an impurity of Lacosamide which is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain and is a potent anticonvulsant. 2-(Acetylamino)-N-(phenylmethyl)-2-propenamide is also used as a reagent in the synthesis of novel N-acyl dehydroalanine derivatives which possess antioxidant properties showing a strong inhibitory effect on lipid peroxidation. | |||
Category: | Amines, Aromatics, Amino Acids & Derivatives, Metabolites & Impurities |