Febuxostat Intermediate A |
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Synonyms: Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate;2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylic Acid Ethyl Ester; Ethyl 2-(4-Hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate | |
Cat. No.: F11035 | CAS No.: 161797-99-5 |
MDL.: | Formula: C13H13NO3S |
F.W.263.31 | Purity: 99% |
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Size/Unit | Price | Qty | Availability | Price Total |
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1mg | POA | Enter qty and click checkbox |
Catalog Number: | F11035 | CAS No.: | 161797-99-5 | |
MDL: | Formula: | C13H13NO3S | ||
F.W.: | 263.31 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | Off-White Solid | M.P.: | 183-184ºC | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Li, X., et. al.: Lett. Org. Chem., 12, 217 (2015); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap | |||
Application: | Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat, a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat w | |||
Category: | Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |