Febuxostat Impurity J |
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Synonyms: Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester; Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate; Febuxostat Ethyl Ester | |
Cat. No.: F11010 | CAS No.: 160844-75-7 |
MDL.: | Formula: C18H20N2O3S |
F.W.344.43 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | F11010 | CAS No.: | 160844-75-7 | |
MDL: | Formula: | C18H20N2O3S | ||
F.W.: | 344.43 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | White to Off-White Solid | M.P.: | 174-176ºC | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO (Slightly), Methanol (Very Slightly, Heated) | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin | |||
Application: | Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat, a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lo | |||
Category: | Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |