Febuxostat |
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Synonyms: 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid; 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic Acid; TEI 6720; TMX 67; | |
Cat. No.: F11000 | CAS No.: 144060-53-7 |
MDL.: | Formula: C16H16N2O3S |
F.W.316.37 | Purity: 99% |
Storage: Refrigerator | |
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Size/Unit | Price | Qty | Availability | Price Total |
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1mg | POA | Enter qty and click checkbox |
Catalog Number: | F11000 | CAS No.: | 144060-53-7 | |
MDL: | Formula: | C16H16N2O3S | ||
F.W.: | 316.37 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | White to Off-White Solid | M.P.: | 208-209°(dec.) | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO, Methanol | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005), | |||
Application: | Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. | |||
Category: | Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |