Celecoxib Intermediate D |
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Synonyms: 4,4,4-Trifluoro-1-(2-methylphenyl)-1,3-butanedione ; 4,4,4-Trifluoro-1-(2-methylphenyl)-1,3-butanedione;1-(2-Methylbenzoyl)-3,3,3-trifluoroacetone | |
Cat. No.: C25528 | CAS No.: 163266-02-2 |
MDL.: | Formula: C11H9F3O2 |
F.W.230.18 | Purity: 99% |
Storage: | |
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Catalog Number: | C25528 | CAS No.: | 163266-02-2 | |
MDL: | Formula: | C11H9F3O2 | ||
F.W.: | 230.18 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Penning, T., et al.: J. Med. Chem., 40, 1347 (1997); Wesolowski, S., et al.: Bioorg. Med. Chem. Lett., 12, 267 (2002) | |||
Application: | 4,4,4-Trifluoro-1-(2-methylphenyl)-1,3-butanedione is a useful synthetic intermediate in the synthesis of 4-Desmethyl-2-methyl Celecoxib ; an analog of Celecoxib which is a cyclooxygenase 2 inhibitor. | |||
Category: | Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |