LDK378 |
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Synonyms: 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine; LDK378;LDK 378 | |
Cat. No.: L98000 | CAS No.: 1032900-25-6 |
MDL.: | Formula: C28H36ClN5O3S |
F.W.558.14 | Purity: 99% |
Storage: | |
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Catalog Number: | L98000 | CAS No.: | 1032900-25-6 | |
MDL: | Formula: | C28H36ClN5O3S | ||
F.W.: | 558.14 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO | Stability: | ||
Storage: | Category: | Reference Standard | ||
Application: | LDK378 is a highly selective, orally bioavailable and ATP-competitive small molecule inhibitor of ALK (Anaplastic Lymphoma Kinase), a receptor tyrosine kinase considered to be an important lung cancer drug target |