IC-87114 |
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Synonyms: 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;IC-87114 | |
Cat. No.: I98000 | CAS No.: 371242-69-2 |
MDL.: | Formula: C22H19N7O |
F.W.397.43 | Purity: 99% |
Storage: | |
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Catalog Number: | I98000 | CAS No.: | 371242-69-2 | |
MDL: | Formula: | C22H19N7O | ||
F.W.: | 397.43 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Application: | IC-87114 was the first isoform-selective PI3K inhibitor :p110M-NM-4(IC50 = 0.13 M-BM-5M) vs. p110M-NM-1(IC50 = 200 M-BM-5M), p110M-NM-2(IC50 = 16 M-BM-5M) and p110M-NM-3(IC50 = 61 M-BM-5M). |