GSK126 |
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Synonyms: (S)-1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide; GSK-126 | |
Cat. No.: G98000 | CAS No.: 1346574-57-9 |
MDL.: | Formula: C31H38N6O2 |
F.W.526.67 | Purity: 99% |
Storage: | |
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Catalog Number: | G98000 | CAS No.: | 1346574-57-9 | |
MDL: | Formula: | C31H38N6O2 | ||
F.W.: | 526.67 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO | Stability: | ||
Storage: | Category: | Reference Standard | ||
Application: | GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity, decreases global H3K27me3 levels and reactivates silenced PRC2 target genes. |