Saxagliptin Impurity B |
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| Synonyms: (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic Acid; (S)-2,3-Dihydropyrrole-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Ethyl Ester ; (S)-2,3-Dihydro-1H-pyrrole-1,2-dicarboxylic acid 1-(1,1-dimethylethyl) 2-Ethyl Ester; (S)-2,3-Dihydropyrrole-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Ethyl Ester | |
| Cat. No.: S12030 | CAS No.: 178172-26-4 |
| MDL.: | Formula: C12H19NO4 |
| F.W.212.25 | Purity: 99% |
| Storage: | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 100mg | $125.00 | Enter qty and click checkbox |
 
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$125.00 |
| Catalog Number： | S12030 | CAS No.: | 178172-26-4 | |
| MDL: | Formula: | C12H19NO4 | ||
| F.W.: | 212.25 | Purity: | 99% | |
| Package: | Unit: | mg | ||
| Appearance: | M.P.: | |||
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | Stability: | |||
| Storage: | Category: | Reference Standard | ||
| Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008), | |||
| Application: | (S)-Boc-2-carbamoyl-2,3-dihydro-1H-pyrrole is an impurity of Saxagliptin, which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | |||
| Category: | Amines, Chiral Reagents, Miscellaneous Reagents | |||