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(2’R,2R,trans)-Saxagliptin

Synonyms: (1S,3R,5S)-2-[(2R)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
Cat. No.: S12004 CAS No.: 1564266-03-0
MDL.: Formula: C18H25N3O2
F.W.315.41 Purity: 99%
Storage:
 
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1mg $5700.00 Enter qty and click checkbox $5700.00
Catalog Number: S12004   CAS No.: 1564266-03-0
MDL: Formula: C18H25N3O2
F.W.: 315.41 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)
Application: (2’R,2R,trans)-Saxagliptin is an impurity of Saxagliptin; a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
Category: Amines, Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals