(2’R,2R,trans)-Saxagliptin |
|
Synonyms: (1S,3R,5S)-2-[(2R)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile | |
Cat. No.: S12004 | CAS No.: 1564266-03-0 |
MDL.: | Formula: C18H25N3O2 |
F.W.315.41 | Purity: 99% |
Storage: | |
  |
Catalog Number: | S12004 | CAS No.: | 1564266-03-0 | |
MDL: | Formula: | C18H25N3O2 | ||
F.W.: | 315.41 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008) | |||
Application: | (2’R,2R,trans)-Saxagliptin is an impurity of Saxagliptin; a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes. | |||
Category: | Amines, Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |