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Saxagliptin

Synonyms: (1S,3S,5S)-2-[(2S)-2-amino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-carbonitrile-13C3; BMS 510849-13C3;
Cat. No.: S12000 CAS No.: 361442-04-8
MDL.: Formula: C18H25N3O2
F.W.315.41 Purity: 99%
Storage: -20˚C Freezer
 
Size/Unit Price Qty Availability Price Total
1mg $140.00 Enter qty and click checkbox $140.00
Catalog Number: S12000   CAS No.: 361442-04-8
MDL: Formula: C18H25N3O2
F.W.: 315.41 Purity: 99%
Package: Unit: mg
Appearance: White Solid M.P.: 107-110°C
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO, Methanol Stability:
Storage: -20˚C Freezer Category: Reference Standard
Reference: Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),
Application: Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
Category: Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals