Saxagliptin |
|
Synonyms: (1S,3S,5S)-2-[(2S)-2-amino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-carbonitrile-13C3; BMS 510849-13C3; | |
Cat. No.: S12000 | CAS No.: 361442-04-8 |
MDL.: | Formula: C18H25N3O2 |
F.W.315.41 | Purity: 99% |
Storage: -20˚C Freezer | |
  |
Catalog Number: | S12000 | CAS No.: | 361442-04-8 | |
MDL: | Formula: | C18H25N3O2 | ||
F.W.: | 315.41 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | White Solid | M.P.: | 107-110°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO, Methanol | Stability: | ||
Storage: | -20˚C Freezer | Category: | Reference Standard | |
Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008), | |||
Application: | Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | |||
Category: | Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |