Felodipine Imtermediate D |
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Synonyms: Ethyl 3-Aminocrotonate; 3-Amino-2-butenoic Acid Ethyl Ester; ß-Aminocrotonic Acid Ethyl Ester; 3-Aminocrotonic Acid Ethyl Ester; Ethyl 3-Amino-2-butenoate; Ethyl ß-Amino-ß-methylacrylate; Ethyl ß-Aminocrotonate; NSC 1086; ß-Aminocrotonic Acid Ethyl Ester | |
Cat. No.: F14018 | CAS No.: 7318-00-5 |
MDL.: | Formula: C6H11NO2 |
F.W.129.16 | Purity: 99% |
Storage: -20°C Freezer | |
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Catalog Number: | F14018 | CAS No.: | 7318-00-5 | |
MDL: | Formula: | C6H11NO2 | ||
F.W.: | 129.16 | Purity: | 99% | |
Package: | Unit: | g | ||
Appearance: | Clear Colourless to Pale Yellow Oil | M.P.: | N/A | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Chloroform, Methanol | Stability: | ||
Storage: | -20°C Freezer | Category: | Reference Standard | |
Reference: | Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. & Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980) | |||
Application: | Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine , a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine, a calcium entry blocker that has antihypertensive properties. | |||
Category: | Amines, Miscellaneous Reagents |