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Felodipine Imtermediate D

Synonyms: Ethyl 3-Aminocrotonate; 3-Amino-2-butenoic Acid Ethyl Ester; ß-Aminocrotonic Acid Ethyl Ester; 3-Aminocrotonic Acid Ethyl Ester; Ethyl 3-Amino-2-butenoate; Ethyl ß-Amino-ß-methylacrylate; Ethyl ß-Aminocrotonate; NSC 1086; ß-Aminocrotonic Acid Ethyl Ester
Cat. No.: F14018 CAS No.: 7318-00-5
MDL.: Formula: C6H11NO2
F.W.129.16 Purity: 99%
Storage: -20°C Freezer
 
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Catalog Number: F14018   CAS No.: 7318-00-5
MDL: Formula: C6H11NO2
F.W.: 129.16 Purity: 99%
Package: Unit: g
Appearance: Clear Colourless to Pale Yellow Oil M.P.: N/A
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Chloroform, Methanol Stability:
Storage: -20°C Freezer Category: Reference Standard
Reference: Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. & Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980)
Application: Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine , a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine, a calcium entry blocker that has antihypertensive properties.
Category: Amines, Miscellaneous Reagents