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Duloxetine Intermediate J

Synonyms: (R)-3-Methylamino-1-(2-thienyl)-1-propanol ; (R)-a-[2-(Methylamino)ethyl]-2-thiophenemethanol; (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol; (R)-(+)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol;
Cat. No.: D80049 CAS No.: 116539-57-2
MDL.: Formula: C9H13NOS
F.W.171.26 Purity: 99%
Storage:
 
Size/Unit Price Qty Availability Price Total
5mg $140.00 Enter qty and click checkbox $140.00
Catalog Number: D80049   CAS No.: 116539-57-2
MDL: Formula: C9H13NOS
F.W.: 171.26 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)
Application: (R)-3-Methylamino-1-(2-thienyl)-1-propanol is a reactant used in the synthesis of enantiomerically pure Duloxetine, an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds