Duloxetine Intermediate J |
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Synonyms: (R)-3-Methylamino-1-(2-thienyl)-1-propanol ; (R)-a-[2-(Methylamino)ethyl]-2-thiophenemethanol; (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol; (R)-(+)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol; | |
Cat. No.: D80049 | CAS No.: 116539-57-2 |
MDL.: | Formula: C9H13NOS |
F.W.171.26 | Purity: 99% |
Storage: | |
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Catalog Number: | D80049 | CAS No.: | 116539-57-2 | |
MDL: | Formula: | C9H13NOS | ||
F.W.: | 171.26 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000) | |||
Application: | (R)-3-Methylamino-1-(2-thienyl)-1-propanol is a reactant used in the synthesis of enantiomerically pure Duloxetine, an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence. | |||
Category: | Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |