| Catalog Number： |
D01001 |
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CAS No.: |
1195768-06-9/1195765-45-7(free amine) |
| MDL: |
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Formula: |
C24H24F3N5O5S3 |
| F.W.: |
615.67 |
|
Purity: |
99％ |
| Package: |
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Unit: |
mg |
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Category: |
Reference Standard |
| Reference: |
Hauschild, A., et al.: Lancet, 380, 358 (2012); Falchook, G.S., et al.: Lancet, 379, 1893 (2012); Ascierto, P.A., et al.: J. Clin. Oncol., 31, 3205 (2013) |
| Application: |
Dabrafenib is an inhibitor of mutated BRAF kinase and has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma. |
| Category: |
Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |
