Abacavir |
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Synonyms: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol | |
Cat. No.: A00001 | CAS No.: 136470-78-5 |
MDL.: | Formula: C14H18N6O |
F.W.286.33 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | A00001 | CAS No.: | 136470-78-5 | |
MDL: | Formula: | C14H18N6O | ||
F.W.: | 286.33 | Purity: | 99% | |
Package: | Unit: | |||
Appearance: | White solid foam from acetonitrile | M.P.: | 165° | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Nucleoside reverse transcriptase inhibitor (NRTI). Prepn: S. M. Daluge, EP 349242 (1990 to Wellcome Found.); idem, US 5034394 (1991 to Burroughs Wellcome). Asymmetric synthesis: M. T. Crimmins, B. W. King, J. Org. Chem. 61, 4192 (1996). Pharmacology and biological profile: S. M. Daluge et al., Antimicrob. Agents Chemother. 41, 1082 (1997). Review of antiviral activity and clinical evaluations: R. H. Foster, D. Faulds, Drugs 55, 729-736 (1998). Clinical trial of triple nucleoside regimen in HIV patients: S. Staszewski et al., J. Am. Med. Assoc. 285, 1155 (2001). | |||
Application: | A nucleoside reverse transcriptase inhibitor (NRTI). Inhibitors | |||
Category: | Antiviral |