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Defactinib (PF-04554878)

Synonyms: N-Methyl-4-[[4-[[[3-[methyl(methylsulfonyl)amino]-2-pyrazinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzamide; VS 6063
Cat. No.: D99600 CAS No.: 1073154-85-4
MDL.: Formula: C20H21F3N8O3S
F.W.510.49 Purity: 99%
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Catalog Number: D99600   CAS No.: 1073154-85-4
MDL: Formula: C20H21F3N8O3S
F.W.: 510.49 Purity: 99%
Package: Unit: mg
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Storage: Category: Reference Standard
Reference: O’Brien, S. et al.: Oncotarget., 5, 7945 (2014); Kang, Y. et al.: J. Natl. Cancer Inst., 105, 1485 (2013);
Application: Defactinib is a selective and orally active FAK inhibitor phase 2. Used in treating cancer patients as it decreases proliferation and increases apoptosis.
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