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GSK126
Synonyms: N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-Indole-4-carboxamide; N-[(4,6-Dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-((1S)-1-methylpropyl)-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
Cat. No.: G00002	CAS No.: 1346574-57-9
MDL.:	Formula: C31H38N6O2
F.W.526.67	Purity: 99％
Storage: Store at 0°C (short term), -20°C (long term)

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Catalog Number：	G00002		CAS No.:	1346574-57-9
MDL:			Formula:	C31H38N6O2
F.W.:	526.67		Purity:	99％
Package:			Unit:	mg
Appearance:	Off-White Solid		M.P.:	>216°C (dec.)
B.P.:			Density:
Optical Rotation:			Refractive Index:
Solubility:	DMSO (Sparingly), Methanol (Sparingly)		Stability:
Storage:	Store at 0°C (short term), -20°C (long term)		Category:	Reference Standard
Reference:	McCabe, M.T., et al.: Nature., 492, 108 (2012);
Application:	GSK126 is a potent and highly selective S-adenosyl-methionine-competitive small molecule inhibitor of EZH2 methyltransferase enzyme activity. The inhibition activity of GSK126 on EZH2 activity may provide a promising treatment for EZH2 mutant lymphoma.
Category:	Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals

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