Catalog Number: |
G00002 |
|
CAS No.: |
1346574-57-9 |
MDL: |
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Formula: |
C31H38N6O2 |
F.W.: |
526.67 |
|
Purity: |
99% |
Package: |
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|
Unit: |
mg |
Appearance: |
Off-White Solid |
|
M.P.: |
>216°C (dec.) |
B.P.: |
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Density: |
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Optical Rotation: |
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Refractive Index: |
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Solubility: |
DMSO (Sparingly), Methanol (Sparingly) |
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Stability: |
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Storage: |
Store at 0°C (short term), -20°C (long term) |
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Category: |
Reference Standard |
Reference: |
McCabe, M.T., et al.: Nature., 492, 108 (2012); |
Application: |
GSK126 is a potent and highly selective S-adenosyl-methionine-competitive small molecule inhibitor of EZH2 methyltransferase enzyme activity. The inhibition activity of GSK126 on EZH2 activity may provide a promising treatment for EZH2 mutant lymphoma. |
Category: |
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |